The left‑leg quadriceps injury to 22‑year‑old Jay Idzes was classified as moderate, ruling him out of the match that kicks off at 20:45 local time, according to the club's medical report.
Coach Roberto De Zerbi confirmed that Duje Caleta‑Car, who featured in the final minutes of Sassuolo's recent draw with Juventus, is ready to replace Idzes and is being considered for a central‑defence role in the starting eleven.
In a separate announcement, Sassuolo extended the contract of back‑room staff member Simone Cinquegrano until 2032, signalling the club's long‑term commitment to its coaching personnel.
Ahead of the fixture, the coaching staff are weighing several lineup options: midfielder Adzic, who scored the winning goal against Juventus, is likely to start; forward Lipani may be left out; goalkeeper Thorstvedt is expected to keep his place, with Bakola as a possible alternative.
The attack will line up in the usual 4‑3‑3 formation, with veteran forwards Domenico Berardi and Lorenzo Laurientè confirmed, while young striker Sebastiano Esposito is favoured over Kieron Bowie for the third attacking spot. Forward Volpato remains unavailable due to injury.
The match will be broadcast live, with a pre‑game video preview available from ANSA, highlighting the tactical adjustments and player availability for both sides.